This study examined the degree to which breast-feeding and cigarette smoking by mothers and smoking by other household members contribute to the exposure of infants to the products of tobacco smoke.
The subjects were 330 mother-infant pairs derived from a cohort of 1000 pairs enrolled in a longitudinal study of the pulmonary effects of prenatal and postnatal smoking.
The main outcome measure was corrected urinary cotinine levels.
Urinary cotinine levels were 10-fold higher in breast-fed infants of smoking mothers than among bottle-fed infants of smoking mothers.
Among infants of nonsmoking mothers, urine cotinine levels were significantly increased in infants living in homes with other smokers ; in this group there was no significant difference between bottle-fed and breast-fed infants.
Infants whose mothers smoked in the same room as the infant had only non-significant increases in cotinine levels compared with infants whose mothers restricted their smoking to other rooms.
Breast-fed infants of smoking mothers have urine cotinine levels 10-fold higher than bottle-fed infants whose mothers smoke, suggesting that breast-feeding, rather than direct inhalation of environmental tobacco smoke, is the primary determinant of cotinine levels in infants whose mothers smoke.
Mots-clés Pascal : Tabagisme passif, Facteur risque, Exposition, Tabac, Pollution air, Tabagisme, Mère, Milieu familial, Allaitement, Exploration toxicologique, Taux, Nicotine, Urine, Nourrisson, Homme, Santé et environnement, Prévention, Etats Unis, Amérique du Nord, Amérique, Etude comparative, Epidémiologie
Mots-clés Pascal anglais : Passive smoking, Risk factor, Exposure, Tobacco, Air pollution, Tobacco smoking, Mother, Family environment, Breast feeding, Toxicological exploration, Rate, Nicotine, Urine, Infant, Human, Health and environment, Prevention, United States, North America, America, Comparative study, Epidemiology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0290708
Code Inist : 002B30A02A. Création : 27/11/1998.