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  1. Relationship between cancer patients'predictions of prognosis and their treatment preferences.

    Article - En anglais

    Context. - Previous studies have documented that cancer patients tend to overestimate the probability of long-term survival.

    If patient preferences about the trade-offs between the risks and benefits associated with alternative treatment strategies are based on inaccurate perceptions of prognosis, then treatment choices may not reflect each patient's true values.


    - To test the hypothesis that among terminally ill cancer patients an accurate understanding of prognosis is associated with a preference for therapy that focuses on comfort over attempts at life extension.


    - Prospective cohort study.


    - Five teaching hospitals in the United States.


    - A total of 917 adults hospitalized with stage III or IV non-small cell lung cancer or colon cancer metastatic to liver in phases 1 and 2 of the Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments (SUPPORT).

    Main Outcome Measures

    - Proportion of patients favoring life-extending therapy over therapy focusing on relief of pain and discomfort, patient and physician estimates of the probability of 6-month survival, and actual 6-month survival.


    - Patients who thought they were going to live for at least 6 months were more likely (odds ratio [OR], 2.6 ; 95% confidence interval [Cl], 1.8-3.7) to favor life-extending therapy over comfort care compared with patients who thought there was at least a 10% chance that they would not live 6 months. (...)

    Mots-clés Pascal : Carcinome, Stade avancé, Etude cohorte, Pronostic, Choix procédé, Traitement, Prospective, Facteur prédictif, Forme clinique, Survie, Etats Unis, Amérique du Nord, Amérique, Homme, Tumeur maligne

    Mots-clés Pascal anglais : Carcinoma, Advanced stage, Cohort study, Prognosis, Process selection, Treatment, Prospective, Predictive factor, Clinical form, Survival, United States, North America, America, Human, Malignant tumor

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0290089

    Code Inist : 002B04F. Création : 27/11/1998.