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  1. Fulltext. Use of urine biomarkers to evaluate menstrual function in healthy premenopausal women.

    Article - En anglais


    A total of 403 healthy, premenopausal women, residing near Santa Clara, California, were recruited from a large health care plan in California for a study of menstrual function.

    After a telephone interview, participants collected daily urine samples and recorded bleeding and other information in diaries.

    Data were collected during 1990-1991.

    Urine samples were analyzed for creatinine and for estradiol and progesterone metabolites by enzyme-linked immunoassay.

    Computer algorithms were developed to derive menstrual segment length, ovulatory status, day of ovulation, and other parameters from the urine and diary data. (We use « segment » rather than « cycle » to avoid implying that normal cycling occurred.) The average length of participation was 141 (standard deviation, 45) days.

    The mean segment length was 28.8 (standard deviation, 4.4) days ; follicular phase length, 16.0 (standard deviation, 4.4) days ; and luteal phase length, 12.9 (standard deviation, 1.7) days ; 19 (4.7%) women experienced anovulatory episodes. (...)

    Mots-clés Pascal : Préménopause, Cycle menstruel, Menstruation, Ovulation, Urine, Algorithme, Méthodologie, Californie, Etats Unis, Amérique du Nord, Amérique, Marqueur biologique, Méthode mesure, Evaluation performance, Homme, Femelle, Epidémiologie, Appareil génital femelle

    Mots-clés Pascal anglais : Premenopause, Menstrual cycle, Menstruation, Ovulation, Urine, Algorithm, Methodology, California, United States, North America, America, Biological marker, Measurement method, Performance evaluation, Human, Female, Epidemiology, Female genital system

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0289385

    Code Inist : 002B24N. Création : 27/11/1998.