This study examined the impact of matemal diabetes on birth weight for gestational age patterns of all term black infants and white infants in the United States using data derived from the 1990-1991 US Live Birth File of the National Center for Health Statistics.
Infants of both black mothers and white mothers exhibited the expected fetal overgrowth associated with matemal diabetes.
However, the increase in birth weight was much greater in infants of black than white diabetic mothers in comparison with their nondiabetic counterparts, as measured by the discrepancy in birth weight between infants of diabetic and nondiabetic mothers at each gestational week, the incidence of large for gestational age, high birth weight, small for gestational age, and low birth weight.
After adjustment for maternal hypertension, prenatal care use, and sociodemographic factors, the disparity in mean birth weight associated with diabetes was 211.67 g in black infants and 115.74 g in white infants.
The adjusted odds ratios of birth weight =4,000 g were 2.98 (95% confidence interval 2.89-3.12) for black infants and 1.83 (95% confidence interval 1.78-1.89) for white infants.
Given the potential risks for mothers and infants consequent to matemal diabetes and fetal hyperinsulinemia, further investigation of the prevalence, characteristics, and outcomes of diabetes during pregnancy among black mothers and infants is warranted.
Mots-clés Pascal : Diabète, Gestation, Ethnie, Négroïde, Caucasoïde, Poids naissance, Age gestation, Macrosomie, Epidémiologie, Facteur risque, Nouveau né, Homme, Etats Unis, Amérique du Nord, Amérique, Malformation, Etude comparative, Endocrinopathie, Gestation pathologie, Foetus pathologie
Mots-clés Pascal anglais : Diabetes mellitus, Pregnancy, Ethnic group, Negroid, Caucasoid, Birth weight, Gestational age, Macrosomia, Epidemiology, Risk factor, Newborn, Human, United States, North America, America, Malformation, Comparative study, Endocrinopathy, Pregnancy disorders, Fetal diseases
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0289384
Code Inist : 002B20F02. Création : 27/11/1998.