To re-analyse the previously reported linear relation between Quetelet's body mass index (BMI) and mortality, among men from the Adventist Mortality Study after accounting for effects due to age at measurement of BMI, smoking history and race.
Prospective cohort study.
To specifically account for effects due to age at measurement of BMI, smoking history and race, our methodology includes :
1, computing hazard ratios for BMI quintiles from a proportional hazard regression, with'time on study'as the time variable, and age at baseline as a covariate ;
2, conducting separate analyses of middle-aged (age 30-54y) and older (age 55-74y) men ;
and 3, restriction of the analyses to never-smoking, non-Hispanic white males.
5062 men (age : 30-74y, BMI : 14-44 kg/m2) from the Adventist Mortality Study.
Subjects reported data on anthropometric, demographic, medical, dietary and lifestyle characteristics at baseline and were enrolled in mortality surveillance during a 26y study period (1960-1985).
During the early years of follow-up (years 1-8,9-14), we found some evidence of excess risk among the leanest men that was probably due to the effects of antecedent illness.
During the later years of follow-up (years 15-26), effects due to antecedent illness were not apparent and a significant positive, linear relation between BMI and all-cause mortality was consistently found among middle-aged (30-54y) and older (55-74y) men. (...)
Mots-clés Pascal : Indice masse corporelle, Mortalité, Fumeur, Age, Etats Unis, Amérique du Nord, Amérique, Antécédent, Etude cohorte, Prospective, Analyse, Homme, Mâle, Adventiste
Mots-clés Pascal anglais : Body mass index, Mortality, Smoker, Age, United States, North America, America, Antecedent, Cohort study, Prospective, Analysis, Human, Male
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0289145
Code Inist : 002B30A01C. Création : 27/11/1998.