Long-term quality of life after kidney and simultaneous pancreas-kidney transplantation.
We are using a validated questionnaire (SF-36) to annually assess health-related quality of life (QOL) in kidney and pancreas-kidney transplant recipients.
The SF-36 consists of eight scales to assess physical functioning, general health and mental functioning.
Norms and 95% confidence intervals (C.I.) have been developed for the US population.
At present. 1138 recipients with functioning grafts (520 Type I diabetic ; 618 nondiabetic) 1-10 yr post-transplant have completed the questionnaire.
Of the recipients, 446 completed the questionnaire once ; 632 twice : and 53 three times (305 after 1 yr ; 266 after 2 yr ; 256 after 3 yr ; 206 after 4 yr ; 192 after 5 yr ; 150 after 6 yr ; 130 after 7 yr ; 138 after 8 yr ; 125 after 9 yr ; 92 after 10 yr).
For both diabetic and nondiabetic recipients, there was little change in average scores for each scale between years (p=NS).
In relation to the US population, average scores for nondiabetics were below the 50th percentile on all 8 scales ; for diabetics<25th, percentile on the physical functioning and vitality scales.<50th percentile on all others.
For both diabetic and nondiabetic recipients, average scores were higher than reported norms for patients with CHF, COPD, or depression but were similar to those with Htn or recent MI.
Individual scores were then compared with age-matched means (±2 SEMs) (95% C.I.) for the US population.
At each year post-transplant. (...)
Mots-clés Pascal : Transplantation, Pancréas, Rein, Exploration clinique, Questionnaire, Evolution, Qualité vie, Santé mentale, Facteur risque, Diabète, Etude statistique, Homme, Chirurgie, Appareil digestif pathologie, Pancréas pathologie, Appareil urinaire pathologie, Rein pathologie, Endocrinopathie
Mots-clés Pascal anglais : Transplantation, Pancreas, Kidney, Clinical investigation, Questionnaire, Evolution, Quality of life, Mental health, Risk factor, Diabetes mellitus, Statistical study, Human, Surgery, Digestive diseases, Pancreatic disease, Urinary system disease, Kidney disease, Endocrinopathy
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0286720
Code Inist : 002B25H. Création : 27/11/1998.