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  1. Clinical trials : study design and analysis : Outcomes research and economic evaluation in radiology.

    Article - En anglais

    To enable doctors to select the best therapeutic strategy, the value of the various options needs to be determined.

    The best approach to the evaluation of therapeutic effectiveness and side effects is a randomised clinical trial.

    Traditionally, such trials have been mainly conducted to evaluate new drugs.

    However, other medical interventions, such as surgical and radiological procedures and lifestyle changes, also require methodologically sound evaluation.

    In this article, some of the basic principles of the study design of randomised clinical trials will be discussed, such as study group comparability, treatment, data collection and statistical analysis, as well as issues relating to randomisation, outcome and blinding.

    Attention is also paid to some of the ethical aspects.

    Mots-clés Pascal : Essai clinique, Traitement, Analyse donnée, Randomisation, Homme

    Mots-clés Pascal anglais : Clinical trial, Treatment, Data analysis, Randomization, Human

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0280603

    Code Inist : 002B30A01A2. Création : 27/11/1998.