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  1. An epidemiologic study of herpes simplex virus type 1 and 2 infection in Japan based on type-specific serological assays.

    Article - En anglais

    A seroepidemiologic study of herpes simplex virus type 1 (HSV-1) and 2 (HSV-2) was performed on Japanese adults.

    Serum samples collected between 1985-9 from a total of 536 healthy adults, female prostitutes, males with sexually transmitted diseases (STD), homosexual men, and pregnant women were studied by immunodot assays using HSV type-specific antigens, glycoproteins G (gG1 and gG2).

    HSV-1 infections correlated mostly with age and was widely prevalent among subjects<40 years.

    HSV-2 prevalence varied greatly among subgroups defined by sexual activity and was associated with risk behaviours for prostitution, infection with STD, and homosexual activity.

    HSV-2 seroprevalence was highest among prostitutes (80%), lowest among pregnant women (7%), and intermediate in STD patients (23%) and homosexuals (24%). Because HSV-I infection during childhood has been decreasing, primary genital HSV-2 infection, with its higher frequency of clinical manifestations, will become a greater burden to the public health in Japan.

    Mots-clés Pascal : Herpesvirus hominis 1, Alphaherpesvirinae, Herpesviridae, Virus, Herpesvirus hominis 2, Prévalence, Homme, Japon, Asie, Epidémiologie, Sérologie

    Mots-clés Pascal anglais : Herpesvirus hominis 1, Alphaherpesvirinae, Herpesviridae, Virus, Herpesvirus hominis 2, Prevalence, Human, Japan, Asia, Epidemiology, Serology

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0271858

    Code Inist : 002A05C06. Création : 27/11/1998.