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  1. Prevalence of Helicobacter pylori infection in a cohort of Italian military students.

    Article - En anglais

    In 1990, to study regional prevalences and risk factors of Helicobacter pylori infection in healthy young adult males, sera were collected from a nationwide sample of 1659 males (mean age 20.7 years) at introduction into the Air Force School for military students in Caserta, Italy.

    An enzyme-linked immunosorbent assay was used to detect H. pylori specific immunoglobulin G antibodies.

    The observed overall seropositivity rate was 17.5% (95% CI 15.7-19.4).

    Prevalence was higher in southern Italy and in the Italian islands as compared with northern Italy and central Italy (21.3% vs. 9.5%). Multiple logistic regression analysis showed that residence in southern areas and islands was the strongest predictor of the likelihood of H. pylori seropositivity ; number of siblings in the household was marginally associated ; years of father's schooling was not a significant predictor.

    H. pylori positive subjects were more likely positive for antibodies to hepatitis A virus infection (anti-HAV) than those H. pylori negative (354% vs. 249% ; Odds Ratio 1.7,95% CI 1.3-2.2).

    Adjustment for the confounding effect of sociodemographic variables weakened this association (OR 1.3,95% CI 1.0-1.7).

    These findings suggest that differences in environmental conditions rather than in socioeconomic status may have played the major role in the different spread of H. pylori infection across the country.

    Mots-clés Pascal : Helicobacter pylori, Spirillaceae, Spirillales, Bactérie, Bactériose, Infection, Homme, Italie, Europe, Militaire, Prévalence, Epidémiologie, Facteur risque, Valeur prédictive, Facteur sociodémographique

    Mots-clés Pascal anglais : Helicobacter pylori, Spirillaceae, Spirillales, Bacteria, Bacteriosis, Infection, Human, Italy, Europe, Military, Prevalence, Epidemiology, Risk factor, Predictive value, Sociodemographic factor

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0271855

    Code Inist : 002A05B12. Création : 27/11/1998.