The opportunity to assess prevalence, incidence, and outcome of schizophrenia and delusional disorder was provided by an age-and sex-stratified random sample of 5,222 persons age 65 years and over.
This sample was chosen from general practitioner lists, and interviewed by psychiatric nurses trained to use the t]eriatric Mental State (GMS) - AGECAT computerized diagnostic system.
GMS-AGECAT ensured the reliability of the selection of cases between the two waves of the study.
A subsample was interviewed by a research psychiatrist.
The sample was followed up 2 years later using the same method by interviewers blind to the initial findings.
The protocols of all nominated cases and subcases of schizophrenia/paranoid disorder diagnosed by AGECAT were reviewed by a clinician and DSM-III-R diagnoses were made.
Refusal rate was 13 percent for initial interviews (wave 1) and 15 percent for reinterview 2 years later (wave 2).
The prevalence of DSM-III-R schizophrenia was 0.12 percent (95% confidence interval [CI] 0.04-0.25) and delusional disorder 0.04 percent (95% CI 0.00-0.14).
The minimum incidence of schizophrenia for new cases was 3.0 (95% CI 0.00 to 110.70) ; for new and relapsed cases, 45.0 (95% CI 3.54-186.20) ; and for delusional disorder, 15.6 (95% CI 0.02-135.10) per 100,000 per year.
Two of the five cases with schizophrenia were known to have been first diagnosed before age 65. (...)
Mots-clés Pascal : Schizophrénie, Incidence, Prévalence, Angleterre, Grande Bretagne, Royaume Uni, Europe, Vieillard, Homme, Association morbide, Evolution, Epidémiologie, Santé mentale, Psychose, Trouble délirant
Mots-clés Pascal anglais : Schizophrenia, Incidence, Prevalence, England, Great Britain, United Kingdom, Europe, Elderly, Human, Concomitant disease, Evolution, Epidemiology, Mental health, Psychosis, Delusional disorder
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0271251
Code Inist : 002B18E. Création : 27/11/1998.