The incidence of hyperthyroidism in Austria from 1987 to 1995 before and after an increase in salt iodization in 1990.
Between 1963 and 1990, Austria had iodized salt prophylaxis of endemic goitre with 10 mg KI (7.5 mg I) per kg.
This was obviously insufficient, as urinary iodine excretion ranged from 42 to 78 mug I per g of creatinine and goitre in adults remained in the endemic range of 15% - 30%. Therefore salt iodization was doubled in 1990.
The aim of this study was to assess the annual incidence of different types of hyperthyroidism (HT) before and after this increase in salt iodization.
The incidence of HT was recorded in 14 nuclear medicine centres from 1987 to 1995.
In five additional centres data were available from 1992 onwards.
Data prior to 1992 were documented retrospectively, while those after 1992 were recorded prospectively.
The 14 centres drew patients from an area with a population of approximately 4.23 million while all 19 institutes were estimated to cover an area with a population of 5.4 million (the total population of Austria is 7.86 million).
A total of 414 232 persons were examined for the first time in the participating centres.
HT and the type of HT were defined by clinical examination, serum TSH, thyroid hormone levels in blood, ultrasonography, scintigraphy and serum auto-antibody titres.
HT was classified into immunogenic HT (Graves'or Basedow's disease, GD) and HT with intrinsic thyroid autonomy (uni-multinodular or disseminated Plummers'disease, PD).
HT was also divided into overt (o) or subclinical (sc) disease (...).
Mots-clés Pascal : Supplémentation, Iode, Sodium chlorure, Incidence, Complication, Iatrogène, Hyperthyroïdie, Symptomatologie, Diagnostic, Scintigraphie, Epidémiologie, Homme, Autriche, Europe, Nutrition, Endocrinopathie, Thyroïde pathologie, Exploration radioisotopique, Imagerie médicale
Mots-clés Pascal anglais : Supplementation, Iodine, Sodium chloride, Incidence, Complication, Iatrogenic, Hyperthyroidism, Symptomatology, Diagnosis, Scintigraphy, Epidemiology, Human, Austria, Europe, Nutrition, Endocrinopathy, Thyroid diseases, Radionuclide study, Medical imagery
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0268078
Code Inist : 002B30A01A2. Création : 11/09/1998.