One hundred and eleven patients with acute hepatitis and 61 controls were investigated for hepatitis serological markers in order to determine the viral etiology of cases involved in a waterborne epidemic of hepatitis observed in 1993 in Djibouti, Republic of Djibouti (East Africa).
These cases occurred both in indigenous Djiboutians, and in French soldiers and their families in Djibouti.
A retrospective study of the viral etiology of acute hepatitis cases observed in French soldiers and relatives living in Djibouti during the 3-year period preceding the epidemic was also undertaken.
HAV, HBV and HCV infections were investigated using commercial ELISA tests.
HEV infections were investigated by testing IgG and IgM-specific antibodies by means of three different ELISA tests using recombinant proteins or synthetic peptides.
Hepatitis A was observed in 37 (33%) and hepatitis E in 43 (39%) of the 111 cases of acute hepatitis recorded during this epidemic.
Hepatitis B represented only 6% of the indigenous cases and hepatitis C was not observed among the cases investigated. (...)
Mots-clés Pascal : Hépatite virale, Virose, Infection, Aigu, Etiologie, Virus hépatite A, Hepatovirus, Picornaviridae, Virus, Virus hépatite B, Orthohepadnavirus, Hepadnaviridae, Virus hépatite E, Calicivirus, Caliciviridae, Distribution, Facteur risque, Origine ethnique, Contamination, Eau, Diagnostic, Epidémiologie, Homme, Djibouti, Afrique, Appareil digestif pathologie, Foie pathologie
Mots-clés Pascal anglais : Viral hepatitis, Viral disease, Infection, Acute, Etiology, Hepatitis A virus, Hepatovirus, Picornaviridae, Virus, Hepatitis B virus, Orthohepadnavirus, Hepadnaviridae, Hepatitis E virus, Calicivirus, Caliciviridae, Distribution, Risk factor, Ethnic origin, Contamination, Water, Diagnosis, Epidemiology, Human, Djibouti, Africa, Digestive diseases, Hepatic disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0266392
Code Inist : 002B05C02G. Création : 11/09/1998.