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  1. Cognitive function and dementia in six areas of England and Wales : the distribution of MMSE and prevalence of GMS organicity level in the MRC CFA Study.

    Article - En anglais


    This two-stage prevalence survey involved geographically delimited areas, four urban (Liverpool, Newcastle, Nottingham and Oxford) and two rural (Cambridgeshire and Gwynedd), including institutions.


    Stratified random population samples of people in their 65th year and above, from Family Health Service Authorities were studied.

    The sample was stratified (65-74 years and = 75) to provide equal numbers.

    In Liverpool equal numbers in 5 year age groups were taken.

    After an initial screening interview, approximately 20% were selected on the basis of age, AGECAT organicity confidence level and MMSE score to proceed to a detailed assessment interview from which the full AGECAT organicity confidence level could be derived.


    Major influences on MMSE were confirmed as age, sex, social class and educational level.

    Estimates of prevalence of AGECAT O3 and above for each centre and the entire sample according to age are given, based on 1991 Census population structure, and suggest that around half a million (543400) people in England and Wales would be defined as case level by this method.

    The five centres employing the same methodology showed no heterogeneity in prevalence.


    Prevalence of cognitive impairment and dementia appear not to vary widely across the centres examined in this study, which provides stable estimates by age and sex for AGECAT O3 and above, and norms for MMSE. (...)

    Mots-clés Pascal : Démence sénile, Prévalence, Incidence, Epidémiologie, Santé mentale, Variation géographique, Angleterre, Grande Bretagne, Royaume Uni, Europe, Pays de Galles, Statut socioéconomique, Sexe, Vieillard, Homme, Système nerveux pathologie, Système nerveux central pathologie, Encéphale pathologie, Maladie dégénérative

    Mots-clés Pascal anglais : Senile dementia, Prevalence, Incidence, Epidemiology, Mental health, Geographical variation, England, Great Britain, United Kingdom, Europe, Wales, Socioeconomic status, Sex, Elderly, Human, Nervous system diseases, Central nervous system disease, Cerebral disorder, Degenerative disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0266044

    Code Inist : 002B17G. Création : 11/09/1998.