Twenty-three patients with Tourette's disorder (13 with obsessive-compulsive symptoms [OCS] and 10 without) were comparatively investigated.
In contrast to OCS-free Tourette's disorder patients, those with OCS were found to be characterized by (i) a higher incidence of volatile temper, (ii) a higher incidence of compulsive tics, (iii) a higher incidence of perinatal disorders and brain wave abnormalities, (iv) a higher severity as rated using the Severity Scale, and (v) a higher prevalence of complications, especially of developmental disorders.
Of the subjects with OCS-accompanied Tourette's disorder, approximately half had developed OCS by the onset of tics.
These findings suggest the likelihood that OCS-accompanied Tourette's disorder is more strongly associated with organic cerebral disorders, independently of sites of tic disorders, than is OCS-free Tourette's disorder.
Mots-clés Pascal : Gilles de la Tourette syndrome, Association morbide, Enfant, Homme, Obsession compulsion, Etude comparative, Trouble développement, Prévalence, Incidence, Epidémiologie, Exploration clinique, Japon, Asie, Système nerveux pathologie, Système nerveux central pathologie, Encéphale pathologie, Maladie dégénérative, Trouble anxieux
Mots-clés Pascal anglais : Gilles de la Tourette syndrome, Concomitant disease, Child, Human, Obsessive compulsive disorder, Comparative study, Developmental disorder, Prevalence, Incidence, Epidemiology, Clinical investigation, Japan, Asia, Nervous system diseases, Central nervous system disease, Cerebral disorder, Degenerative disease, Anxiety disorder
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0265921
Code Inist : 002B17G. Création : 11/09/1998.