Occupational asthma is common, yet little is known about long-term outcomes in the United States.
A case series of 55 (of 72) occupational asthma patients were interviewed in follow-up 31 (± 15) months after removal from the cause to evaluate asthma severity and employment outcomes.
Standard criteria were used to rate severity.
At follow-up, 54 subjects (98%) had active asthma, of which 26 cases (47%) were « severe. » Multivariate analysis showed increased risk of « severe » asthma for women (odds ratio [OR]=13.8 ; 95% confidence interval [95% CI]=1.3 to 151.7) and industrial sector workers (OR=11.9 ; 95% CI=1.3 to 109.8).
Thirty-eight subjects (69%) were unemployed, risk being greater for those with « severe » asthma (OR=20.9 ; 95% CI=1.9 to 229.8) and for those without a college degree (OR=7.3 ; 95% CI=1.2 to 43.4).
These results indicate that occupational asthma is disabling and probably irreversible for most patients referred to a specialty clinic, despite prolonged removal from causative agents.
Women, industrial workers, and those with severe asthma or lack of a college degree appear to be at risk for worse outcomes.
Greater efforts at primary and secondary prevention should lessen the burden of long-term illness and unemployment due to occupational asthma.
Mots-clés Pascal : Asthme, Exposition professionnelle, Indice gravité, Long terme, Pronostic, Incapacité travail, Durée, Médecine travail, Impact socioéconomique, Homme, Appareil respiratoire pathologie, Bronchopneumopathie obstructive, Allergie, Immunopathologie
Mots-clés Pascal anglais : Asthma, Occupational exposure, Severity score, Long term, Prognosis, Work disability, Duration, Occupational medicine, Socioeconomical impact, Human, Respiratory disease, Obstructive pulmonary disease, Allergy, Immunopathology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0265424
Code Inist : 002B11B. Création : 11/09/1998.