Workplace risk factors for cancer in the German rubber industry : part 1. Mortality from respiratory cancers.
Objectives-To determine the cancer specific mortality by work area among active and retired male workers in the German rubber industry.
Methods-A cohort of 11 663 male German workers was followed up for mortality from 1 January 1981 to 31 December 1991.
Cohort members were classified as active (n=7536) or retired (n=4127) as of 1 January 1981 and had been employed for at least one year in one of five study plants producing tyres or technical rubber goods.
Work histories were reconstructed with routinely documented « cost centre codes » which were classified into six categories :
I preparation of materials ;
II production of technical rubber goods ;
III production of tyres ;
IV storage and dispatch ;
V maintenance ;
and VI others.
Standardised mortality ratios (SMRs) adjusted for age and calendar year and 95% confidence intervals (95% CIs), stratified by work area (employment in respective work area for at least one year) and time related variables (year of hire, lagged years of employment in work area), were calculated from national reference rates.
SMRs for laryngeal cancer were highest in work area I (SMR 253 ; 95% CI 93 to 551) and were significant among workers who were employed for>10 years in this work area (SMR 330 ; 95% CI 107 to 779).
Increased mortality rates from lung cancer were identified in work areas I (SMR 162 ; 95% CI 129 to 202), II (SMR 134 ; 95% CI 109 to 163), and V (SMR 131 ; 95% CI 102 to 167). (...)
Mots-clés Pascal : Tumeur maligne, Bronchopulmonaire, Larynx, Plèvre, Epidémiologie, Exposition professionnelle, Carcinogène, Milieu professionnel, Industrie caoutchouc, Mortalité, Homme, Allemagne, Europe, Médecine travail, Etude cohorte, Appareil respiratoire pathologie, Poumon pathologie, Bronche pathologie, ORL pathologie, Larynx pathologie, Plèvre pathologie, Activité professionnelle, Facteur risque
Mots-clés Pascal anglais : Malignant tumor, Bronchopulmonary, Larynx, Pleura, Epidemiology, Occupational exposure, Carcinogen, Occupational environment, Rubber industry, Mortality, Human, Germany, Europe, Occupational medicine, Cohort study, Respiratory disease, Lung disease, Bronchus disease, ENT disease, Larynx disease, Pleural disease, Professional activity, Risk factor
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0263594
Code Inist : 002B11A. Création : 11/09/1998.