Cutaneous vasculitis in a defined population - clinical and epidemiological associations.
Objective, To examine the value of the American College of Rheumatology (ACR) 1990 criteria for Henoch-Schönlein purpura (HSP) and hypersensitivity vasculitis (HSV) and the Chapel Hill Consensus Conference (CHCC) definition of cutaneous leukocytoclastic angiitis (CLA) in the classification of cutaneous vasculitis and to estimate the annual incidence of biopsy proven cutaneous vasculitis in a well defined population.
ACR criteria for HSP and HSV and the CHCC definition for CLA and HSP were applied to an unselected cohort of 84 patients with biopsy proven cutaneous vasculitis attending a single district hospital in the United Kingdom between January 1990 and December 1994.
Thirty-seven patients fulfilled ACR criteria for HSV, of whom 27 also fulfilled the ACR criteria for HSP.
Thirty-two patients met the CHCC definition for CLA and 7 the CHCC definition for HSP.
The overall annual incidence of cutaneous vasculitis was 38.6/million (95% Cl 30.6-48.1), and for CLA 15.4/million (95% Cl 10.6-21.8).
The ACR 1990 criteria for HSP and HSV overlap ; the CHCC definitions for CLA and HSP provide clearer distinction.
Cutaneous vasculitis is as common as systemic vasculitis.
Mots-clés Pascal : Vascularite, Allergie, Vascularite leucocytoclasique, Purpura rhumatoïde, Symptomatologie, Association morbide, Classification, Exploration immunologique, Exploration cytologique, Résultat, Homme, Peau pathologie, Immunopathologie, Appareil circulatoire pathologie, Vaisseau sanguin pathologie, Capillaire sanguin pathologie, Système ostéoarticulaire pathologie
Mots-clés Pascal anglais : Vasculitis, Allergy, Leucocytoclastic vasculitis, Henoch-Schönlein purpura, Symptomatology, Concomitant disease, Classification, Immunological investigation, Cytologic investigation, Result, Human, Skin disease, Immunopathology, Cardiovascular disease, Vascular disease, Capillary vessel disease, Diseases of the osteoarticular system
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0260106
Code Inist : 002B07. Création : 11/09/1998.