Objectives This study estimated the risk of occupational exposure for lung cancer in the metropolitan region of Silo Paulo, the largest urbanized and industrialized area in Brazil.
Methods In this hospital-based case-referent study of 398 cases and 860 referents, the cases were matched to referents according to age, gender, and hospital and personally interviewed for information on lifetime job history, smoking habits, passive smoking exposure, cancer in relatives, socioeconomic status, and migratory history.
The analysis concerned industrial titles and occupational categories.
With the use of a job-exposure matrix, exposure to asbestos, polynuclear aromatic hydrocarbons, arsenic, dust, nickel and chromium was assessed.
Results For the men in the 56 industrial and 122 occupational categories examined, an excess risk of lung cancer was found in the machinery industry [odds ratio (OR) 1.62,95% confidence interval (95% CI) 1.022.55).
In pottery manufacturing the risk (OR 2.21,95% CI 1.00-4.87) was increased for workers exposed =10 years (OR 6.43,95% CI 1.12-37.01).
Textile workers employed for<10 years with a latency of =40 years had an elevated risk (OR 21.93,95% CI 1.96-245.0).
In the analysis using the job-exposure matrix no risk was detected for the specific lung cancer carcinogens examined.
For the women, no significantly elevated risk was observed. (...)
Mots-clés Pascal : Tumeur maligne, Bronchopulmonaire, Homme, Facteur risque, Epidémiologie, Exposition professionnelle, Catégorie socioprofessionnelle, Industrie, Carcinogène, Composé chimique, Brésil, Amérique du Sud, Amérique, Médecine travail, Appareil respiratoire pathologie, Poumon pathologie, Bronche pathologie, Matrice emploi exposition
Mots-clés Pascal anglais : Malignant tumor, Bronchopulmonary, Human, Risk factor, Epidemiology, Occupational exposure, Socioeconomic category, Industry, Carcinogen, Chemical compound, Brazil, South America, America, Occupational medicine, Respiratory disease, Lung disease, Bronchus disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0258716
Code Inist : 002B11A. Création : 11/09/1998.