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  1. Familial patterns in birth characteristics : impact on individual and population risks.

    Article - En anglais

    Background Familial patterns in reproductive outcome have been suggested previously, but few studies have comprehensively evaluated both length of gestation and types of growth retardation.

    Methods Information on intrauterine period and birth characteristics for a cohort of Swedish women born 1955-1972 was linked with information on these women's own reproductive experiences during 1973-1990.

    Familial trends in preterm deliveries, small-for-gestational age (SGA) births and two types of growth retardation were evaluated for mothers relative to their own birth characteristics (n=4746), relative to their older sisters'deliveries (n=2931) and among consecutive deliveries of the mothers (n=14 209).

    Adjusted relative risks (RR) were calculated from logistic regression analyses.

    Results Mothers who had themselves been preterm at birth were not at increased risk of any of the outcomes studied.

    Mothers who had themselves been SGA at birth had an almost 50% higher risk (NS) of giving birth to either a preterm or an SGA infant than had mothers who had not been SGA at birth.

    Mothers tended to repeat the same patterns in subsequent deliveries : RR was 3.7 for a second preterm delivery given a previous one and 7.8 for a second SGA delivery given a previous one.

    Among SGA siblings, chronic growth retardation was more often repeated than was acute growth retardation. (...)

    Mots-clés Pascal : Hypotrophie foetale, Prématurité, Gestation pathologie, Milieu familial, Epidémiologie, Facteur risque, Nouveau né, Homme, Suède, Europe, Etude cohorte, Foetus pathologie

    Mots-clés Pascal anglais : Intrauterine growth retardation, Prematurity, Pregnancy disorders, Family environment, Epidemiology, Risk factor, Newborn, Human, Sweden, Europe, Cohort study, Fetal diseases

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0251613

    Code Inist : 002B20F02. Création : 11/09/1998.