Fungal infection in critically ill patients is an increasingly prevalent problem.
Candida spp. cause the majority of these infections in ICU.
They occur most commonly in patients with severe underlying illness, multiple courses of antibiotics and intravascular catheters.
Clinical diagnosis is difficult due to nonspecific signs and the frequent occurrence of widespread superficial colonization with Candida spp. in ventilated patients.
Most patients are diagnosed using inferential evidence of infection, such as persistent pyrexia despite antibiotics, raised serum C-reactive protein and the presence of individual risk factors.
Amphotericin B and fluconazole are the most commonly used anti-fungals dependent on the identity of the fungus.
Most of these infections are endogenous ; however, a proportion may be caused via the hands of healthcare staff or contaminated medical equipment.
Mots-clés Pascal : Candidose, Mycose, Infection, Unité soin intensif, Antifongique, Antiinfectieux, Facteur risque, Etiologie, Diagnostic, Chimiothérapie, Traitement, Homme, Article synthèse, Soin intensif, Service hospitalier
Mots-clés Pascal anglais : Candidiasis, Mycosis, Infection, Intensive care unit, Antifungal agent, Antiinfectious, Risk factor, Etiology, Diagnosis, Chemotherapy, Treatment, Human, Review, Intensive care, Hospital ward
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0251362
Code Inist : 002B05D02L. Création : 11/09/1998.