The purpose of this study was to estimate the risk of small-for-gestational-age birth by levels of nicotine in the hair of mothers and offspring.
In a sample of 58 case subjects and 105 control subjects, hair nicotine concentrations were measured by gas chromatography and mass spectrometry.
With women whose hair nicotine concentrations were in the lowest quartile as the reference group, the odds ratio (OR) for small-for-gestational-age birth was increased among women with concentrations in the upper and two middle quartiles (OR=4.2,95% confidence interval [CI]=1.5,11.5, and OR=3.2,95% CI=1.3,8.0).
When smoking mothers were excluded from the analysis, the corresponding odds ratios were 2.1 (95% CI=0.4,10.1) and 3.4 (95% CI=1.3,8.6).
The results suggest that passive maternal smoking increases the risk of small-for-gestational-age births.
Mots-clés Pascal : Hypotrophie foetale, Dysmaturité foetale, Non fumeur, Mère, Tabagisme passif, Nicotine, Cheveu, Toxicité, Epidémiologie, Analyse quantitative, Taux, Facteur risque, Nouveau né, Homme, Prévention, Etude cas témoin, Santé et environnement, Gestation pathologie, Foetus pathologie, Norvège, Europe
Mots-clés Pascal anglais : Intrauterine growth retardation, Fetal dysmaturity, Non smoker, Mother, Passive smoking, Nicotine, Hair (head), Toxicity, Epidemiology, Quantitative analysis, Rate, Risk factor, Newborn, Human, Prevention, Case control study, Health and environment, Pregnancy disorders, Fetal diseases, Norway, Europe
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0251229
Code Inist : 002B20F02. Création : 11/09/1998.