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  1. Short-term effect of winter air pollution on respiratory health of asthmatic children in paris.

    Article - En anglais

    There is controversy as to whether low levels of air pollution affect the symptoms and lung function in asthma.

    We addressed this by examining the short-term effects of winter air pollution on childhood asthma in Paris.

    We performed a 6 month follow-up of 84 medically diagnosed asthmatic children classified into two groups of severity.

    The outcomes included incidence and prevalence of asthma attacks, symptoms and use of supplementary bêta2-agonists, peak expiratory flow (PEF) value and its variability.

    The statistical analysis controlled the lack of independence between daily health outcomes, trends and meteorology, Air pollution was associated with an increase in reports and duration of asthma attacks and asthma-like symptoms in mild asthmatic children.

    The strongest association was the risk of asthma attack for an increase of 50 mug-m-3 of sulphur dioxide (SO2) on the same day (odds ratio (OR)=2.86).

    Maximum reduction in morning peak expiratory flow (PEF) (5%) and maximum increase in PEF variability (2%) were observed at a lag of 3 days for an increase of 50 mug. m-3 of SO2 in the subgroup of mild asthmatics receiving no regular inhaled medication.

    In moderate asthmatic children, the duration of supplementary bêta2-agonist use was strongly associated with air pollution.

    The general pattern of our results provides evidence of the effect of the low levels of air pollution encountered in Western Europe on symptoms and lung function in childhood asthma.

    Mots-clés Pascal : Asthme, Pollution air, Milieu urbain, Hiver, Fonction respiratoire, Paris, Ile de France, France, Europe, Exploration, Epidémiologie, Enfant, Homme, Appareil respiratoire pathologie, Bronchopneumopathie obstructive

    Mots-clés Pascal anglais : Asthma, Air pollution, Urban environment, Winter, Lung function, Paris, Ile-de-France, France, Europe, Exploration, Epidemiology, Child, Human, Respiratory disease, Obstructive pulmonary disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0247175

    Code Inist : 002B11B. Création : 11/09/1998.