Increased risk of spastic diplegia among very low birth weight children after preterm labor or prelabor rupture of membranes.
Our objective was to study the association of spastic diplegia (SDP ; N=29) with the initiator of preterm birth in a regional cohort of 312 6-year-old very low birth weight children (<=1500 gm).
We determined the prevalence of SDP among those children born after idiopathic preterm onset of labor (POOL) or prelabor rupture of membranes (PROM) (12% SDP). and among those born after pregnancy-induced hypertension or other medical indications for preterm delivery (4% SDP).
Stratification showed that 83% of the children with diplegia were born after POOL or PROM.
The threefold increased risk of SDP among those children born after POOL or PROM compared with the remainder of the cohort (crude odds ratio 3.2,95% confidence interval 1.2 to 8.5) remained elevated after controlling for perinatal and neonatal variables (odds ratio 2.4 to 2.7) in logistic regression models We conclude that birth after POOL or PROM increases the risk of SDP among very low birth weight children and speculate that this might be related to infectious processes leading to both POOL or PROM and SDP.
Mots-clés Pascal : Diplégie, Hypertonie spastique, Facteur risque, Rupture prématurée membrane foetoplacentaire, Poids naissance faible, Dépistage, Prévalence, Nourrisson, Homme, Allemagne, Europe, Système nerveux pathologie, Trouble neurologique, Trouble moteur, Gestation pathologie, Accouchement pathologie
Mots-clés Pascal anglais : Diplegia, Spasticity, Risk factor, Premature rupture of membrane, Low birth weight, Medical screening, Prevalence, Infant, Human, Germany, Europe, Nervous system diseases, Neurological disorder, Motor system disorder, Pregnancy disorders, Delivery disorders
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0245785
Code Inist : 002B17I. Création : 11/09/1998.