To compare the prevalence of Raynaud's phenomenon (RP) in 2 genetically different ethnic groups in Estonia : Estonians, who are Finno-Ugric people, and Slavs, who are Indo-European people, and to investigate the risk factors of RP.
A random sample of 5248 Estonians and 4341 Slavs were surveyed by mail questionnaire (Phase I) for suspected RP.
A subsample of 1739 subjects was interviewed and examined (Phase II) to make a formal diagnosis of RP, using the color charts. and to collect additional pertinent information.
Of these 1739 subjects examined in Phase II, 226 women and 162 men were diagnosed to have RP.
The age adjusted prevalence of RP was significantly higher among Slavs (women 11.4 ± 1.3%, men 13.0 ± 1.6%) compared to Estonians (women 7.8 ± 1.0%, p=0.023 ; men 8.2 ± 1.5%, p=0.031).
Based on logistic regression analysis, the diagnosis of RP among women was associated with a Slavic ethnic origin, the presence of connective tissue disorders or cardiovascular diseases, a family history of RP, a history of dysphagia and frostbite. smoking, and a lower body mass index (BMI).
Among men RP was associated with manual work, vibrating tool use, a history of frostbite and injuries to the fingers, older age, and a lower BMI.
Our results revealed a significant difference in the prevalence of RP between 2 ethnic groups living in the same geographic region. (...)
Mots-clés Pascal : Raynaud syndrome, Pathogénie, Homme, Epidémiologie, Prévalence, Facteur risque, Etude comparative, Ethnie, Estonie, Europe Est, Europe, Appareil circulatoire pathologie, Vaisseau sanguin pathologie, Capillaire sanguin pathologie, Peau pathologie, Système nerveux autonome pathologie, Acrosyndrome
Mots-clés Pascal anglais : Raynaud phenomenon, Pathogenesis, Human, Epidemiology, Prevalence, Risk factor, Comparative study, Ethnic group, Estonia, Eastern Europe, Europe, Cardiovascular disease, Vascular disease, Capillary vessel disease, Skin disease, Diseases of the autonomic nervous system, Acrosyndrome
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0238411
Code Inist : 002B12B03. Création : 11/09/1998.