logo BDSP

Base documentaire

  1. A comprehensive clinical epidemiological theory based on the concept of the source person-time and four distinct study stages.

    Article - En anglais

    The medical community is forced to accelerate the move from opinion-based to evidence-based medicine, that is, to aim at basing all caring and clinical practice on empiri.

    A clear-cut epistemology would facilitate this process.

    In this article we present a comprehensive clinical epidemiological theory which can be used for validity issues in caring science, quality of life research. controlled clinical trials and compilations of uncontrolled evidence.

    The theory is based on four distinct stages that can be identified in a study, whereof the first is demarcation of the source person-time.

    A source person-time ('study base') can be identified for any study in all disciplines, giving an argument for using this concept as the common reference point for validity issues.

    Apart from identifying the source person-time, recovery of the actually observed person-time, collection of data and calculation of an ('adjusted') effect parameter (e.g., incidence ratio) are additional stages of a study.

    When the source person-time is demarcated confounding is introduced, when the actually observed person-time is recovered misrepresentation, in the third stage misclassification and in the fourth analytical alteration of the parameter of effect. (...)

    Mots-clés Pascal : Epidémiologie, Théorie, Concept, Article synthèse

    Mots-clés Pascal anglais : Epidemiology, Theory, Concept, Review

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0233084

    Code Inist : 002B30A01A1. Création : 11/09/1998.