Nested case-control study of tumors of the hemopoietic and lymphatic systems among workers in the meat industry.
Workers in the meat industry are exposed to viruses that cause leukemia and lymphoma in cattle and chickens, and also to carcinogenic chemical agents.
This case-control study, nested in a cohort of members of a meatcutters'union in Baltimore, Maryland, investigated whether occupational exposures are associated with death from tumors of the hemopoietic and lymphatic systems.
Cases of these tumors represent all deaths which occurred in the cohort between 1949 and 1980.
Excess risks of tumors of the hemopoietic and lymphatic systems were observed throughout the meat industry, except in meatpacking plants.
Slaughtering activities involving heavy exposure to oncogenic viruses were strongly associated with these tumors, especially with lymphomas.
Thus, elevated risks were observed for butchers who killed animals (odds ratio (OR)=5.3,95% confidence interval (Cl) 1.0-27.0) ; workers in chicken-slaughtering plants (OR=3.3,95% Cl 0.8-13.1) ; and workers in cattle/sheep/pig abattoirs (OR=2.8,95% CI 0.8-9.5).
Among supermarket workers, wrapping meat (mainly a female activity) was associated with increased risk of tumors of the hemopoietic and lymphatic systems (OR=3.8,95% Cl 1.0-14.3), with the odds of both lymphomas and tumors of the myeloid stem cell being elevated.
On the other hand, meatcutting in supermarkets (almost exclusively a male activity) was associated with multiple myeloma ; the odds ratio for men was 18.0 (95% Cl 1.6-207. (...)
Mots-clés Pascal : Leucémie, Myélome, Lymphome, Exposition professionnelle, Activité professionnelle, Virus, Produit chimique, Toxicité, Industrie alimentaire, Viande, Animal, Epidémiologie, Facteur risque, Homme, Médecine travail, Etats Unis, Amérique du Nord, Amérique, Etude cas témoin, Hémopathie maligne, Lymphoprolifératif syndrome, Immunopathologie, Immunoglobulinopathie
Mots-clés Pascal anglais : Leukemia, Myeloma, Lymphoma, Occupational exposure, Professional activity, Virus, Chemical product, Toxicity, Food industry, Meat, Animal, Epidemiology, Risk factor, Human, Occupational medicine, United States, North America, America, Case control study, Malignant hemopathy, Lymphoproliferative syndrome, Immunopathology, Immunoglobulinopathy
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0232750
Code Inist : 002B19B. Création : 11/09/1998.