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  1. Modern life'in the epidemiology of inflammatory bowel disease : a case-control study with special emphasis on nutritional factors.

    Article - En anglais

    Objective The rising incidence of inflammatory bowel disease (IBD) since the Second World War coincides with profound changes of the dietary pattern.

    The aim of the study was to investigate the possible pathogenic role of some characteristic'modern life'dietary factors in IBD.

    Design Case-control, studying risk factors in recently diagnosed cases, 290 with Crohn's disease and 398 with ulcerative colitis, compared with 616 population controls.

    Smoking, age, gender and education were taken into account by using logistic regression analysis.

    Setting Hospital cases and population controls

    Interventions Questionnaires.

    Main outcome measures Logistic regression-derived odds ratios.

    Results A positive association with cola drinks [OR : 2.2 (95% Cl 1.5-3.1) ], chewing gum [OR : 1.5 (95% Cl : 1.1-2.1) ] and chocolate consumption [OR : 2.5 (95% Cl : 1.8-3.5) 1 and a negative association with citrus fruit consumption [OR : 0.5 (95% Cl 0.3-0.7) 1 and the development of Crohn's disease were found.

    Consumption of cola drinks [OR : 1.6 (95% Cl 1.1-2.3) ] and chocolate consumption [OR : 2.5 (95% CI 1.8-3.5) ] were positively associated with developing ulcerative colitis.

    There was a negative association between the intake of citrus fruits [OR : 0.5 (95% CI 0.4-0.8) ] and'having a stuffed pet'for a period longer than 5 years [OR : 0.6 (95% CI 0.4-0.9) ] and developing the disorder.

    No association with the frequency of tooth brushing and developing IBD was found. (...)

    Mots-clés Pascal : Rectocolite ulcérohémorragique, Entérite Crohn, Relation, Augmentation, Incidence, Habitude alimentaire, Tabagisme, Sexe, Statut socioéconomique, Epidémiologie, Homme, Appareil digestif pathologie, Intestin pathologie, Maladie inflammatoire, Nutrition, Toxicomanie

    Mots-clés Pascal anglais : Ulcerative colitis, Crohn disease, Relation, Increase, Incidence, Food habit, Tobacco smoking, Sex, Socioeconomic status, Epidemiology, Human, Digestive diseases, Intestinal disease, Inflammatory disease, Nutrition, Drug addiction

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0230458

    Code Inist : 002B13B03. Création : 11/09/1998.