The results of three published randomized controlled trials of fecal occult blood testing (FOBT) provide unequivocal proof of the principle that screening reduces mortality from colorectal cancer (CRC).
However, several interesting questions remain in interpreting and applying the results of the clinical trials, including : how well does FOBT screening work (i.e. how much can CRC mortality be reduced), how does it work, when is it worthwhile and worthwhile doing, and how can technique be optimized ?
The answers to these questions have important practical and clinical implications.
Mots-clés Pascal : Carcinome, Côlon, Rectum, Dépistage, Asymptomatique, Fèces, Hémorragie, Méthodologie, Evaluation performance, Métaanalyse, Homme, Tumeur maligne, Appareil digestif pathologie, Intestin pathologie, Côlon pathologie, Rectum pathologie, Equipement biomédical, Appareil circulatoire pathologie, Vaisseau sanguin pathologie
Mots-clés Pascal anglais : Carcinoma, Colon, Rectum, Medical screening, Asymptomatic, Feces, Hemorrhage, Methodology, Performance evaluation, Metaanalysis, Human, Malignant tumor, Digestive diseases, Intestinal disease, Colonic disease, Rectal disease, Biomedical equipment, Cardiovascular disease, Vascular disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0230450
Code Inist : 002B13B01. Création : 11/09/1998.