To determine the prevalence of asthma and chronic obstructive pulmonary disease in patients not known to have these disorders, who present in general practice with persistent cough, and to ascertain criteria to help general practitioners in diagnosis.
Primary healthcare centre in the Netherlands.
192 patients aged 18-75 years, not known to have asthma or chronic obstructive pulmonary disease, attending their general practitioner with cough persisting for at least 2 weeks.
A diagnosis of asthma or chronic obstructive pulmonary disease was based on the recurrence of airway symptoms in the past year accompanied by spirometric measurements (including bronchodilator testing) and methacholine provocation tests.
A scoring formula to estimate the probability of asthma or chronic obstructive pulmonary disease, based on history and physical examination, was generated by means of logistic regression.
74 patients (39%) were classified as having asthma, 14 (7%) as having chronic obstructive pulmonary disease.
The best formula for predicting asthma or chronic obstructive pulmonary disease used scores for three symptoms : (reported) wheeze, (reported) dyspnoea, and allergen induced symptoms, together with prolonged expiration, pack years of smoking, and female sex.
Variables were scored 1 when present and () when absent, except for allergen induced symptoms. (...)
Mots-clés Pascal : Toux, Diagnostic, Etiologie, Asthme, Bronchopneumopathie obstructive, Chronique, Exploration clinique, Facteur risque, Critère sélection, Etude statistique, Homme, Appareil respiratoire pathologie, Poumon pathologie, Trachée pathologie, Bronche pathologie, Trouble respiratoire
Mots-clés Pascal anglais : Cough, Diagnosis, Etiology, Asthma, Obstructive pulmonary disease, Chronic, Clinical investigation, Risk factor, Selection criterion, Statistical study, Human, Respiratory disease, Lung disease, Diseases of the trachea, Bronchus disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0230118
Code Inist : 002B11B. Création : 11/09/1998.