We conducted a cross-sectional epidemiological study to evaluate personal exposure to nitrogen dioxide and its effect on blood antioxidants.
Personal exposure of 107 volunteers was assessed for 14 d with passive monitors.
We excluded heavy smokers (>10 cigarettes/d) from the study.
Sociodemographic and environmental data, as well as bêta-carotene intake, were recorded.
We mainly attributed the mean nitrogen dioxide personal exposure (31.9 ± 12.7 mug/m3 [0.017 ppm or 0.70 muM/m3]) (R2=0.75) to residence site in the city, time spent in urban traffic, and use of gas stoves.
The correlation between nitrogen dioxide exposure and blood antioxidant concentration was weak ; in addition, the correlation coefficients for men and women were inconsistent.
Nonetheless, we found some evidence of an interaction between carotene intake and nitrogen dioxide exposure : a significantly lower plasma bêta-carotene level was evident among subjects who consumed<4.5 mg/jour of carotene and who were exposed to nitrogen dioxide levels that exceeded 40 mug/m3 (0.021 ppm or 0.87 muM/m3) of nitrogen dioxide.
Mots-clés Pascal : Azote dioxyde, Polluant, Air, Toxicité, Epidémiologie, Homme, Antioxydant, Plasma sanguin, Sang, Bétacarotène, Marqueur biologique, Pollution air, France, Europe
Mots-clés Pascal anglais : Nitrogen dioxide, Pollutant, Air, Toxicity, Epidemiology, Human, Antioxidant, Blood plasma, Blood, Betacarotene, Biological marker, Air pollution, France, Europe
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0229598
Code Inist : 002B03M02. Création : 11/09/1998.