Missing data in quality of life research in Eastern Cooperative Oncology Group (ECOG) clinical trials : Problems and solutions.
Workshop on Missing Data in Quality of Life Research in Cancer Clinical Trials : Practical and Methodological Issues. Bad Horn, CHE, 1996/07/01.
Incorporation of quality of life (QOL) investigation into Eastern Cooperative Oncology Group (ECOG) multi-centre clinical trials has led to innovative strategies for protocol design and high quality data collection.
A scientific advisory committee reviews protocol design components, measurement selection, timing of assessments and compliance issues.
Extensive educational programmes provide information about the scientific and clinical relevance of QOL protocols, as well as practical strategies for data collection and management.
Compliance with QOL data collection standards is prospectively monitored and evaluated.
Preliminary results from eight ECOG-run protocols found overall compliance to be approximately 85 per cent (94 per cent at baseline and 73 per cent during treatment).
Selected patient and institutional factors were evaluated for their association with compliance.
Mots-clés Pascal : Méthode analyse, Donnée manquante, Qualité vie, Essai clinique, Etude multicentrique, Homme, Programme enseignement, Méthodologie, Cancérologie, Tumeur maligne
Mots-clés Pascal anglais : Analysis method, Missing data, Quality of life, Clinical trial, Multicenter study, Human, Educational program, Methodology, Cancerology, Malignant tumor
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0228430
Code Inist : 002B30A01A2. Création : 11/09/1998.