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  1. Stachybotrys, a mycotoxin-producing fungus of increasing toxicologic importance.

    Article - En anglais


    Stachybotrys as a fungus has been implicated as a source of mycotoxins.

    While the toxicity of several well-known mycotoxins (aflatoxins) is well documented, recent studies on Stachybotrys have raised the question that mycotoxins produced by this fungus may be responsible for the health effects of occupants in water-damaged buildings.


    Published artides regarding Stachybotrys-related mycotoxins were reviewed with particular focus on human toxicity.


    A critical review of papers, reports, and studies on Stachybotrys mycotoxins revealed only descriptive reports of suspected animal and human poisoning secondary to consumption of mold-contaminated food products.

    No studies of good toxicologic and epidemiologic designs answer whether airborne mycotoxins produced by Stachybotrys could produce specific human toxicity.


    Current data on the toxicology of mycotoxins produced by Stachybotrys demonstrate that this group of mycotoxins is capable of producing immunosuppression and inflammatory insults to gastrointestinal and pulmonary systems.

    Case control study and case reports have suggested a possible association with environmental exposure to Stachybotrys mycotoxins, although a firm causal relationship has not been firmly established.

    Additional studies are needed to document that humans with sufficient exposure to these mycotoxins develop compatible clinical and pathologic pictures as demonstrated in animal models.

    Mots-clés Pascal : Stachybotrys, Fungi Imperfecti, Fungi, Thallophyta, Stachybotryotoxicose, Mycotoxine, Article synthèse, Toxicité, Homme, Animal, Epidémiologie, Immunodépression, Humidité, Pollution air, Pollution intérieur, Immunopathologie, Appareil digestif pathologie, Appareil respiratoire pathologie

    Mots-clés Pascal anglais : Stachybotrys, Fungi Imperfecti, Fungi, Thallophyta, Stachybotryotoxicosis, Mycotoxin, Review, Toxicity, Human, Animal, Epidemiology, Immunosuppression, Humidity, Air pollution, Indoor pollution, Immunopathology, Digestive diseases, Respiratory disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0227012

    Code Inist : 002B03J. Création : 11/09/1998.