A 10-year retrospective survey was undertaken of patients with pyogenic hepatic abscesses (PHA).
Fifty-two patients fulfilled the criteria of PHA, equivalent to a mean annual incidence of 11/1,000,000.
The main symptom was fever.
Laboratory tests were compatible with infection, slightly elevated alkaline phosphatase being the only test pointing towards the liver as the focus of infection.
Forty-one patients (79%, 95% CL, 68-90%) had positive cultures from aspirated pus, with a total of 79 isolates.
Enteric Gram-negative rods accounted for 45% and anaerobic bacteria for 31% of PHA isolates.
Gram-positive cocci, predominantly non-haemolytic streptococci, were the third largest group (19%), but were rare among blood isolates.
Positive blood cultures were found in 21 patients (40%, 95% CL, 27-54%), with a total of 28 isolates.
Percutaneous drainage was performed in 26, percutaneous needle aspiration in 10, combinations thereof in 5, and abdominal surgery in 5. Forty-nine patients received systemic antibiotic therapy, four of whom were treated with antibiotics only.
Seven recurrences occurred and the overall case fatality rate was 6% (95%, CL 0-12%), which might reflect a low rate of underlying malignant diseases in our study material.
Mots-clés Pascal : Abcès, Foie, Pyogène, Incidence, Epidémiologie, Danemark, Europe, Bactériose, Infection, Etiologie, Traitement, Pronostic, Homme, Appareil digestif pathologie, Foie pathologie
Mots-clés Pascal anglais : Abscess, Liver, Pyogenic, Incidence, Epidemiology, Denmark, Europe, Bacteriosis, Infection, Etiology, Treatment, Prognosis, Human, Digestive diseases, Hepatic disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0226573
Code Inist : 002B05B02F. Création : 11/09/1998.