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  1. Autopsy-verified venous thromboembolism within a defined urban population : the city of Malmö, Sweden.

    Article - En anglais

    Objective

    To analyse the frequency of autopsy-proven venous thromboembolism within a defined region and evaluate if certain risk groups not earlier recognized could be found.

    The incidence of objectively diagnosed venous thromboembolism was also calculated.

    Setting

    The city of Malmö, Sweden, with 230,000 inhabitants.

    Main outcome measure

    Analysis of 2,356 autopsies for the year 1987 of deceased inhabitants from the city of Malmö (2,981 deceased, autopsy frequency 79.0'K>) regarding venous thromboembolism.

    Results

    25% of autopsies revealed venous thromboembolism.

    At the acute-care hospital 31%, at the chronic hospital 37%, but in forensic autopsies of non-hospital deaths only 5% (p<0.001) revealed venous thromboembolism.

    Major pulmonary embolism was seen in 13% and was more frequent in in-hospital deaths (p<0.001).

    Two in-hospital and two non-hospital deaths due to pulmonary embolism and fractures were found : two patients with knee fractures, one hip fracture and one ankle fracture patient.

    The incidence of objectively diagnosed venous thromboembolism (autopsy, phlebography, perfusion scintigraphy) was calculated and an incidence of 42.5/10,000 inhabitants/year was found, (strongly age-dependent).

    Conclusion

    Venous thromboembolism is a common finding in autopsies of hospitalized patients.

    Patients with fractures other than hip fractures are less well studied as regards venous thromboembolic complications.

    Further studies on these fracture patients are warranted.

    Mots-clés Pascal : Thrombose profonde, Veine, Thromboembolie, Embolie pulmonaire, Incidence, Autopsie, Epidémiologie, Suède, Europe, Homme, Appareil circulatoire pathologie, Vaisseau sanguin pathologie, Veine pathologie, Appareil respiratoire pathologie, Médecine légale

    Mots-clés Pascal anglais : Deep vein thrombosis, Vein, Thromboembolism, Pulmonary embolism, Incidence, Autopsy, Epidemiology, Sweden, Europe, Human, Cardiovascular disease, Vascular disease, Venous disease, Respiratory disease, Legal medicine

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0226570

    Code Inist : 002B12B03. Création : 11/09/1998.