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  1. Blood thiamin status and determinants in the population of Seychelles (Indian Ocean).

    Article - En anglais

    Study objective-Micronutrient deficiencies have become rare in industrialised countries as availability of fresh food, supplementation, and fortification have improved but a less favourable situation may still prevail in many developing countries.

    Blood thiamin status and determinants were therefore investigated in the Seychelles in view of the high incidence of dilated cardiomyopathy and as the staple diet is polished rice that is deficient in thiamin.

    Design-This was a cross sectional population study using an age and sex stratified random sample.

    Setting-Seychelles Islands (Indian Ocean)

    Participants-A subsample of 206 subjects aged 25-64 years from the population of Seychelles.

    Main outcome measures-Measurement of total thiamin concentration in whole blood using high performance liquid chromatography.

    Dietary variables measured using a face to face semi-quantitative food questionnaire.


    Mean (SD) whole blood thiamin concentration was 77.9 (22.4) nmo/l and low concentration (<70 nmol/l) was found in 37% of the subjects (95% CI : 31%, 44%). Blood thiamin was significantly related to education and diet but not to age, sex, smoking, and body mass index.

    Blood thiamin was associated positively with meat, vegetable, salad, and tea intake and negatively with alcohol and fish intake.

    However, no combination of the examined variables could explain more than 15% of the observed variance in blood thiamin values. (...)

    Mots-clés Pascal : Thiamine, Plasma sanguin, Taux, Déficit, Cardiomyopathie, Epidémiologie, Facteur risque, Incidence, Homme, Seychelles, Iles Océan Indien, Appareil circulatoire pathologie, Cardiopathie, Myocarde pathologie

    Mots-clés Pascal anglais : Thiamine, Blood plasma, Rate, Deficiency, Cardiomyopathy, Epidemiology, Risk factor, Incidence, Human, Seychelles, Indian Ocean Islands, Cardiovascular disease, Heart disease, Myocardial disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0224178

    Code Inist : 002B12A05. Création : 11/09/1998.