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  1. Longterm survey (7 years) in a population at risk for Lyme borreliosis : What happens to the seropositive individuals ?

    Article - En anglais

    In 1986, a 26% seroprevalence of IgG-anti-Borrelia burgdorferi antibodies was observed among 950 orienteers and the incidence of new clinical infections was 0.8%. In 1993, a total of 305 seropositive orienteers were reexamined.

    During that time, 15 cases (4.9%) of definite/probable Lyme disease occurred in this seropositive group (12 skin manifestations and 3 monoarticular joint manifestations).

    Among the 12 definite cases, 9 showed new clinical infections (7 EM, 1 acrodermatitis chronica atrophicans, 1 arthritis), and 3 were recurrent (2 EM, 1 arthritis).

    The annual incidence (0.8%) in this seropositive group was identical to the incidence observed among the whole population in 1986.

    The individual antibody titer decreased slightly but the seroreversion rate was low (7%). Serology was not very helpful in identifying clinical cases and evolutions, and it can be stated, that a positive serology is much more frequent in this risk group than clinical disease.

    Mots-clés Pascal : Lyme maladie, Borréliose, Spirochétose, Bactériose, Infection, Borrelia burgdorferi, Spirochaetaceae, Spirochaetales, Bactérie, Anticorps, Surveillance sanitaire, Epidémiologie, Prévalence, Sérologie, Homme, Suisse, Europe

    Mots-clés Pascal anglais : Lyme disease, Borrelia infection, Spirachaetosis, Bacteriosis, Infection, Borrelia burgdorferi, Spirochaetaceae, Spirochaetales, Bacteria, Antibody, Sanitary surveillance, Epidemiology, Prevalence, Serology, Human, Switzerland, Europe

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0222799

    Code Inist : 002B05B02L6. Création : 11/09/1998.