Background The prognostic value of exercise thallium-201 imaging has been well established in referral patient populations at tertiary care centers, but these results may be influenced by referral bias.
Methods This study was performed to evaluate the prognostic value of thallium imaging in a community-based population of 446 residents of Olmsted County, Minn.
Eleven variables were prospectively selected and tested for their associations with outcome end points.
Results Four variables (age, history of myocardial infarction, number of abnormal thallium segments on the postexercise images, and increased thallium lung uptake) contained the most independent prognostic information.
For the end point overall mortality rate, the multivariate chi-square values were 17.2 (p<0.0001) for age and 20.9 (p<0.0001) for the number of abnormal thallium segments on the postexercise images.
Five-year survival rate for patients older than the median age of 59 years with an abnormal scan was 84% versus 97% for patients <=59 years of age with a normal scan.
Conclusion Exercise thallium imaging was useful for prognostic purposes in this relatively low-risk community population, confirming the findings of referral population studies.
Mots-clés Pascal : Tomoscintigraphie, Homme, Pronostic, Facteur prédictif, Santé communautaire, Population, Epreuve effort, Facteur risque, Epidémiologie, Exploration, Sensibilité, Spécificité, Exploration radioisotopique, Thallium 201
Mots-clés Pascal anglais : Emission tomography, Human, Prognosis, Predictive factor, Community health, Population, Exercise tolerance test, Risk factor, Epidemiology, Exploration, Sensitivity, Specificity, Radionuclide study
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0218369
Code Inist : 002B24B04. Création : 11/09/1998.