Background This study tests the hypothesis that epilepsy increases the risk of developing schizophrenia and other non-affective functional psychoses using a nationwide sample of people with epilepsy.
Method A record linkage study between a sample from the National Patient Register, consisting of 67 116 16 people with epilepsy, and the Danish Psychiatric Register identified all people with non-affective psychoses with onset after the first epilepsy diagnosis.
The relation between risk of psychiatric disorder in people with epilepsy and the general Danish population was estimated.
Results The incidences ofthe spectrum of non organic non-affective psychosis, non-affective psychosis and schizophrenia were significantly increased both for men and women, even after exclusion of people diagnosed as suffering from a learning disability or substance misuse.
Conclusion This study supports the notion ofan association between epilepsy and the risk of subsequent non-affective psychosis.
Mots-clés Pascal : Epilepsie, Facteur risque, Schizophrénie, Epidémiologie, Danemark, Europe, Incidence, Santé mentale, Homme, Système nerveux pathologie, Système nerveux central pathologie, Encéphale pathologie, Psychose
Mots-clés Pascal anglais : Epilepsy, Risk factor, Schizophrenia, Epidemiology, Denmark, Europe, Incidence, Mental health, Human, Nervous system diseases, Central nervous system disease, Cerebral disorder, Psychosis
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0211417
Code Inist : 002B18C06A. Création : 11/09/1998.