Quality of life in persons with irritable bowel syndrome : Development and validation of a new measure.
How irritable bowel syndrome (IBS) and its treatment affect quality of life (QOL) is important.
To develop a quality-of-life measure specific to irritable bowel syndrome, items were generated using a conceptual model and qualitative interviews with persons diagnosed using the Rome criteria.
Symptom frequency and bothersomeness indices were created.
Psychometric evaluation methods involved an initial cross-sectional survey followed by a repeat survey.
The resulting 34-item measure demonstrated high internal consistency (Cronbach's alpha=0.95) and high reproducibility (ICC=0.86) with average time of seven days (sD=1).
For discriminant validity : number of symptoms (P<0.05), self-reported severity of symptoms (P<0.001), and the functional bowel disorder severity index (P<0.001) significantly predicted IBS-QOL scores.
Convergent validity and analyses confirmed predictions that scores are more closely related to psychological well-being (0.45) than to function (0.36).
We conclude this measure meets established psychometric criteria for reliability and validity ; testing of its responsiveness is warranted.
Mots-clés Pascal : Côlon irritable, Exploration clinique, Qualité vie, Questionnaire, Echelle évaluation, Evaluation performance, Homme, Appareil digestif pathologie, Intestin pathologie
Mots-clés Pascal anglais : Irritable bowel syndrome, Clinical investigation, Quality of life, Questionnaire, Evaluation scale, Performance evaluation, Human, Digestive diseases, Intestinal disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0207293
Code Inist : 002B13B03. Création : 11/09/1998.