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  1. Mortality from asthma and cancer among sulfite mill workers.

    Article - En anglais

    Objectives The aims of the present case-referent study were to investigate whether sulfite workers show increased mortality from asthma, chronic obstructive pulmonary disease or certain malignancies of interest in relation to sulfite mill work.

    The main exposure from the pulping processes is from sulfur dioxide, wood dust and terpenes.

    Methods The subjects of the study were all the men who died between 1960 and 1989 and who were aged 40 to 75 years at death (N=780) in the parishes surrounding 3 sulfite mills.

    The men who died from asthma (N=13), COPD (N=20), lung cancer (N=33), stomach cancer (N=35), or brain tumor (N=10) formed the case group.

    All the subjects, except the cases in question, were used as referents.

    As a proxy variable of exposure, job titles from the registers of deaths and burials were used, and 24% of the subjects were classified as exposed.

    Results There was an increased mortality from asthma [odds ratio (OR) 2.8,90% confidence interval (90% Cl) 1.1-6.8] and brain tumors (OR 3.3,90% Cl 1.2-8.9) among the sulfite workers.

    The mortality due to lung cancer was not significantly increased (OR 1.4,90% Cl 0.7-2.6), and there was a reduced mortality from stomach cancer (OR 0.4,90% Cl 0.2-4.9).

    Conclusions The increased asthma mortality may be due to accidental exposure to irritating gases, such as sulfur dioxide.

    The increased risk for brain tumors has no obvious explanation.

    Mots-clés Pascal : Asthme, Tumeur maligne, Bronchopulmonaire, Estomac, Encéphale, Mortalité, Epidémiologie, Pâte sulfite, Industrie papier, Papeterie, Exposition professionnelle, Homme, Soufre dioxyde, Poussière, Terpène, Suède, Europe, Appareil respiratoire pathologie, Bronchopneumopathie obstructive, Poumon pathologie, Bronche pathologie, Estomac pathologie, Appareil digestif pathologie, Système nerveux central pathologie, Système nerveux pathologie, Encéphale pathologie, Toxicité, Médecine travail

    Mots-clés Pascal anglais : Asthma, Malignant tumor, Bronchopulmonary, Stomach, Brain (vertebrata), Mortality, Epidemiology, Sulfite pulp, Paper industry, Paper mill, Occupational exposure, Human, Sulfur dioxide, Dust, Terpene, Sweden, Europe, Respiratory disease, Obstructive pulmonary disease, Lung disease, Bronchus disease, Gastric disease, Digestive diseases, Central nervous system disease, Nervous system diseases, Cerebral disorder, Toxicity, Occupational medicine

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0201776

    Code Inist : 002B03L02. Création : 11/09/1998.