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  1. Risk factors for benign breast disease according to histopathological type : Comparisons with risk factors for breast cancer.

    Article - En anglais

    We evaluated risk factors for benign breast disease by using a case-control study method.

    The series was taken from participants in breast cancer screening programs during 1978-1986 in Miyagi Prefecture, Japan.

    All benign breast lesions diagnosed during this period were reviewed and reclassified into proliferative and non-proliferative types based on the Dupont and Page classification.

    Data on 382 benign breast disease cases (130 proliferative-type cases and 252 non-proliferative-type cases) and 1,489 screening year-age-and screening area-matched normal controls were used for analysis.

    Nulliparity or low parity and family history of breast cancer in mother or sisters were significantly associated with an increased risk of proliferative type.

    Pre-menopausal status was significantly associated with an increased risk of non-proliferative type.

    No significant association with history of lactation for the last child was observed in either type, but the risk of proliferative type increased with increasing duration of lactation (P=0.08).

    A comparison between the present findings and the risk factors for breast cancer indicated epidemiologic similarities between proliferative benign and malignant breast lesions in general.

    The associations of these two lesions with lactation patterns were, however, dissimilar.

    Mots-clés Pascal : Tumeur maligne, Glande mammaire, Facteur risque, Hyperplasie, Lésion précancéreuse, Lactation, Fibroadénome, Préménopause, Nulliparité, Lipome, Epidémiologie, Japon, Asie, Etude comparative, Etude cas témoin, Type histologique, Histopathologie, Homme, Glande mammaire pathologie, Tumeur bénigne, Anatomopathologie, Tissu adipeux pathologie

    Mots-clés Pascal anglais : Malignant tumor, Mammary gland, Risk factor, Hyperplasia, Premalignant lesion, Lactation, Fibroadenoma, Premenopause, Nulliparity, Lipoma, Epidemiology, Japan, Asia, Comparative study, Case control study, Histological type, Histopathology, Human, Mammary gland diseases, Benign neoplasm, Pathology, Adipose tissue disorders

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0196836

    Code Inist : 002B20E02. Création : 11/09/1998.