Following an accidental release of nitrogen dioxide from a railroad tank car containing nitrous tetroxide, the authors undertook a study of the health effects of the release, measuring the association between acute ow level exposure and pulmonary symptoms.
The authors reviewed the records of three emergency departments, surveyed 80 emergency department patients, 552 community residents, 21 chemical plant workers, and 29 emergency workers, and conducted a case-contro study.
Pulmonary case status was defined as having an objective pulmonary finding noted on the emergency departmert record, reporting that the onset of symptoms was subsequent to the release, and being within the city limits at the time of the release.
Self-reported case status was defined as reporting one or more symptoms consistent with exposure to nitrogen dioxide in the week after the release and having been within the city limits at the time of the release.
Control subjects were survey respondents who reported no symptoms in the week after the release and had been within the city limits at the time of the release.
Chemical exposure was characterized by proximity to, direction from, and being outdoors within one hour after the release.
Duration of potentia exposure was not measured.
Logistic regression was used to estimate odds ratios and 95% confidence intervals for symptoms by exposure level, adjusted for age, sex, smoking, and preexisting pulmonary conditions.
Mots-clés Pascal : Intoxication, Dépistage, Accident, Azote dioxyde, Etude comparative, Complication, Insuffisance respiratoire, Facteur risque, Homme, Etats Unis, Amérique du Nord, Amérique, Article synthèse, Toxicologie, Gaz, Appareil respiratoire pathologie
Mots-clés Pascal anglais : Poisoning, Medical screening, Accident, Nitrogen dioxide, Comparative study, Complication, Respiratory failure, Risk factor, Human, United States, North America, America, Review, Toxicology, Gases, Respiratory disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0196629
Code Inist : 002B03L02. Création : 11/09/1998.