Capsular polysaccharide types of group B streptococcal isolates from neonates with early-onset systemic infection.
The distribution of serotypes of group B streptococci (GBS) isolated from 67 infants with early-onset sepsis are described.
Case-infants were assembled from 13 hospitals across the United States from 15 July 1995 to 5 February 1997 through prospective active surveillance.
The distribution of GBS serotypes was Ia, 40% ; Ib, 9% ; II, 6% ; III, 27% ; V, 15% ; and nontypeable, 3%. Type V occurred more frequently in the northeast region (New York and New Jersey) than in other regions (29% vs. 9%, P=06).
Conversely, type III occurred significantly less frequently in the northeast region than other regions (10% vs. 35%, P=04).
GBS types Ia, III, and V accounted for 82% of the isolates.
This report supports previous observations about the emergence of GBS type V, but our data caution that conclusions about serotype distributions based on one geographic location or on a small number of patients may not be generally applicable.
Continued monitoring seems necessary for the design of a GBS vaccine.
Mots-clés Pascal : Streptococcus B, Streptococcaceae, Micrococcales, Bactérie, Isolat clinique, Nouveau né, Homme, Etats Unis, Amérique du Nord, Amérique, Caractérisation, Phénotype, Capsule microorganisme, Polyoside, Sérotype, Streptococcie, Bactériose, Infection, Epidémiologie, Systémique
Mots-clés Pascal anglais : Streptococcus B, Streptococcaceae, Micrococcales, Bacteria, Clinical isolate, Newborn, Human, United States, North America, America, Characterization, Phenotype, Microorganism capsule, Polysaccharide, Serotype, Streptococcal infection, Bacteriosis, Infection, Epidemiology, Systemic
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0174791
Code Inist : 002A05B11. Création : 11/09/1998.