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  1. Sample size calculations in economic evaluations.

    Article - En anglais

    Traduction en français : Calcul de la taille de l'échantillon dans les évaluations économiques.

    A simulation method is presented for sample size calculation in economic evaluation.

    As input the method requires :

    The expected difference and variance of costs and effects, their correlation, the significance level and the power of the testing method and the maximum acceptable ratio of incremental effectiveness to incremental costs The method is illustrated with data from two trials.

    The first compare primary coronary angioplasty with streptokinase in the treatment of acute myocardial infarction, in the second trial, lansoprazole is compared with omeprazole in the treatment of reflux oesophagitis.

    These case studies show how the vaious parameters influence the sample size.

    Mots-clés Pascal : Aspect économique, Evaluation, Echantillon, Traitement, Méthodologie, Modèle, Etude cas

    Mots-clés Pascal anglais : Economic aspect, Evaluation, Sample, Treatment, Methodology, Models, Case study

    Notice produite par :
    CREDES - Centre de Recherche, d'Etudes et de Documentation en Economie de la Santé (devenu IRDES)

    Cote : 15900, P173

    Code Inist : 002B30A11. Création : 11/09/1998.