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  1. Structural changes in male trapezius muscle with work-related myalgia.

    Article - En anglais

    Muscular changes in male forest machine operators with work-related neck and shoulder myalgia were studied.

    Enzyme cyto-and immunohistochemical analysis was carried on muscle biopsies obtained from ten myalgic subjects (M), nine non-myalgic selected in the same work place (NM) and six healthy young men (C).

    The M group displayed a significant increase in type IIA fibres in comparison to the C group.

    This hypertrophy was accompanied by a parallel increase in the capillary bed.

    Both the M and NM groups exhibited an increase in fibres with a disorganised mitochondrial pattern.

    Interestingly, fibres lacking cytochrome c oxidase occurred in the M group (0.9%) but also in the NM group (0.5%), suggesting a mitochondrial defect.

    Central nuclei (5.2%) and developmental myosin (3%) were also more frequent in the M group.

    These changes are probably related to injury-regeneration cycles.

    These data support the association between the work conditions and muscle changes in work-related trapezius myalgia.

    Mots-clés Pascal : Myalgie, Cou, Epaule, Travail, Immunohistochimie, Muscle trapèze, Fibre musculaire, Ultrastructure, Cytochrome-c oxidase, Oxidoreductases, Enzyme, Médecine travail, Etude comparative, Physiopathologie, Exploration, Adulte, Homme, Mâle, Douleur, Muscle strié pathologie, Anatomopathologie

    Mots-clés Pascal anglais : Myalgia, Neck, Shoulder, Labour, Immunohistochemistry, Trapezius muscle, Muscular fiber, Ultrastructure, Cytochrome-c oxidase, Oxidoreductases, Enzyme, Occupational medicine, Comparative study, Pathophysiology, Exploration, Adult, Human, Male, Pain, Striated muscle disease, Pathology

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0171435

    Code Inist : 002B17H. Création : 21/07/1998.