This study was undertaken to determine the relationship between fetal fibronectin, short cervix, bacterial vaginosis, other traditional risk factors, and spontaneous preterm birth.
From 1992 through 1994,2929 women were screened at the gestational age of 22 to 24 week.
The odds ratios for spontaneous preterm birth were highest for fetal fibronectin, followed by a short cervix and history of preterm birth.
These factors, as well as bacterial vaginosis, were more strongly associated with early than with late spontaneous pretenn birth.
Bacterial vaginosis was more common-and a stronger predictor of spontaneous preterm birth-in Black women, while body mass index less than 19.8 was a stronger predictor m non-Black women.
This analysis suggests a pathway leading from Black race through bacterial vaginosis and fetal fibronectin to spontaneous preterm birth.
Prior preterm birth is associated with spontaneous preterm birth through a short cervix.
Fetal fibronectin and a short cervix are stronger predictors of spontaneous preterm birth than traditional risk factors.
Bacterial vaginosis was found more often in Black than in non-Black women and accounted for 40% of the attributable risk for spontaneous preterm birth at less than 32 weeks.
Mots-clés Pascal : Prématurité, Epidémiologie, Prédiction, Facteur risque, Nouveau né, Homme, Angleterre, Grande Bretagne, Royaume Uni, Europe
Mots-clés Pascal anglais : Prematurity, Epidemiology, Prediction, Risk factor, Newborn, Human, England, Great Britain, United Kingdom, Europe
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0150601
Code Inist : 002B20F02. Création : 21/07/1998.