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  1. Fulltext. Cryptosporidium in tap water : Comparison of predicted risks with observed levels of disease.

    Article - En anglais


    Waterbome transmission of Cryptosporidium parvum is well-established as a source in outbreaks of cryptosporidiosis ; however, the role of tap water in endemic disease is unclear.

    The authors applied a risk assessment approach incorporating uncertainty analysis to examine the potential role of tap water in the transmission of endemic C. parvum infection.

    The model had two components : exposure-infection, to relate low-dose exposure to infection ; and infection-outcome, to include the probabilities of clinical outcomes leading to case detection and reporting.

    The population was divided into four subgroups : adults and children with and without acquired immunodeficiency syndrome (AIDS).

    Because of the high degree of uncertainty associated with available measures, a plausible baseline concentration of oocysts, 1 per 1,000 liters, was assumed for input to the model.

    In the non-AIDS subgroups, the predicted median annual risk of infection was approximately 1 in 1,000 (non-AIDS adults : 0.0009 infection/person/year, 95% confidence interval (CI) 0.0003-0.0028), while in the AIDS subgroups the predicted risk was 2 in 1,000 (AIDS adults : 0.0019 infection/person/year, 95% Cl 0.0003-0.0130).

    When the risks were applied to the 1995 New York City population, more than 6,000 infections were estimated, with 99% occurring in the non-AIDS categories. (...)

    Mots-clés Pascal : Cryptosporidium parvum, Apicomplexa, Protozoa, Cryptosporidiose, Protozoose, Parasitose, Infection, Eau alimentation, Eau distribution, Contamination, Epidémiologie, Facteur risque, Analyse statistique, Homme, Etats Unis, Amérique du Nord, Amérique

    Mots-clés Pascal anglais : Cryptosporidium parvum, Apicomplexa, Protozoa, Cryptosporidiosis, Protozoal disease, Parasitosis, Infection, Feed water, Tap water, Contamination, Epidemiology, Risk factor, Statistical analysis, Human, United States, North America, America

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0149383

    Code Inist : 002B05E02B9. Création : 21/07/1998.