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  1. Risk factors for 5-year mortality in older adults : The cardiovascular health study.

    Article - En anglais

    Context. - Multiple factors contribute to mortality in older adults, but the extent to which subclinical disease and other factors contribute independently to mortality risk is not known.

    Objective

    - To determine the disease, functional, and personal characteristics that jointly predict mortality in community-dwelling men and women aged 65 years or older.

    Design

    - Prospective population-based cohort study with 5 years of follow-up and a validation cohort of African Americans with 4.25-year follow-up.

    Setting

    - Four US communities.

    Participants

    - A total of 5201 and 685 men and women aged 65 years or older in the original and African American cohorts, respectively.

    Main Outcome Measures

    - Five-year mortality.

    Results

    - In the main cohort, 646 deaths (12%) occurred within 5 years.

    Using Cox proportional hazards models, 20 characteristics (of 78 assessed) were each significantly (P<. 05) and independently associated with mortality : increasing age, male sex, income less than $50 000 per year, low weight, lack of moderate or vigorous exercise, smoking for more than 50 pack-years, high brachial (>169 mm Hg) and low tibial (¾127 mm Hg) systolic blood pressure, diuretic use by those without hypertension or congestive heart failure, elevated fasting glucose level (>7.2 mmol/L [130 mg/dL]), low albumin level (¾37 g/L), elevated creatinine level (=106 mumol/L [1.2 mg/dL]), low forced vital capacity. (...)

    Mots-clés Pascal : Vieillard, Homme, Dépistage, Etude cohorte, Facteur risque, Mortalité, Etiopathogénie, Noir américain, Evaluation, Organisation santé

    Mots-clés Pascal anglais : Elderly, Human, Medical screening, Cohort study, Risk factor, Mortality, Etiopathogenesis, Black American, Evaluation, Public health organization

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 98-0144608

    Code Inist : 002B30A03B. Création : 21/07/1998.