Context. - Multiple factors contribute to mortality in older adults, but the extent to which subclinical disease and other factors contribute independently to mortality risk is not known.
- To determine the disease, functional, and personal characteristics that jointly predict mortality in community-dwelling men and women aged 65 years or older.
- Prospective population-based cohort study with 5 years of follow-up and a validation cohort of African Americans with 4.25-year follow-up.
- Four US communities.
- A total of 5201 and 685 men and women aged 65 years or older in the original and African American cohorts, respectively.
- Five-year mortality.
- In the main cohort, 646 deaths (12%) occurred within 5 years.
Using Cox proportional hazards models, 20 characteristics (of 78 assessed) were each significantly (P<. 05) and independently associated with mortality : increasing age, male sex, income less than $50 000 per year, low weight, lack of moderate or vigorous exercise, smoking for more than 50 pack-years, high brachial (>169 mm Hg) and low tibial (¾127 mm Hg) systolic blood pressure, diuretic use by those without hypertension or congestive heart failure, elevated fasting glucose level (>7.2 mmol/L [130 mg/dL]), low albumin level (¾37 g/L), elevated creatinine level (=106 mumol/L [1.2 mg/dL]), low forced vital capacity. (...)
Mots-clés Pascal : Vieillard, Homme, Dépistage, Etude cohorte, Facteur risque, Mortalité, Etiopathogénie, Noir américain, Evaluation, Organisation santé
Mots-clés Pascal anglais : Elderly, Human, Medical screening, Cohort study, Risk factor, Mortality, Etiopathogenesis, Black American, Evaluation, Public health organization
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0144608
Code Inist : 002B30A03B. Création : 21/07/1998.