Community-acquired methicillin-resistant Staphylococcus aureus in children with no identified predisposing risk.
Context. - Community-acquired methicillin-resistant Staphylococcus aureus (MRSA) infections in children have occurred primarily in individuals with recognized predisposing risks.
Community-acquired MRSA infections in the absence of identified risk factors have been reported infrequently.
To determine whether community-acquired MRSA infections in children with no identified predisposing risks are increasing and to define the spectrum of disease associated with MRSA isolation.
- Retrospective review of medical records.
- Hospitalized children with S aureus isolated between August 1988 and July 1990 (1988-1990) and between August 1993 and July 1995 (1993-1995).
- The University of Chicago Children's Hospital.
Main Outcome Measures
- Prevalence of community-acquired MRSA over time, infecting vs colonizing isolates, and risk factors for disease.
- The number of children hospitalized with community-acquired MRSA disease increased from 8 in 1988-1990 to 35 in 1993-1995.
Moreover, the prevalence of community-acquired MRSA without identified risk increased from 10 per 100000 admissions in 1988-1990 to 259 per 100000 admissions in 1993-1995 (P<. 001), and a greater proportion of isolates produced clinical infection.
The clinical syndromes associated with MRSA in children without identified risk were similar to those associated with community-acquired methicillin-susceptible S aureus. (...)
Mots-clés Pascal : Staphylococcus aureus, Micrococcaceae, Micrococcales, Bactérie, Résistance traitement, Communauté, Méticilline, Facteur prédictif, Rétrospective, Prévalence, Enfant, Homme, Pénicilline dérivé, Bactériose, Infection, Antibactérien, Antibiotique
Mots-clés Pascal anglais : Staphylococcus aureus, Micrococcaceae, Micrococcales, Bacteria, Negative therapeutic reaction, Community, Meticillin, Predictive factor, Retrospective, Prevalence, Child, Human, Penicillin derivatives, Bacteriosis, Infection, Antibacterial agent, Antibiotic
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0143886
Code Inist : 002B05B02N. Création : 21/07/1998.