Nordic Symposium on Trace Elements in Human Health and Disease. Roskilde, DNK, 1997/06/29.
Molybdenum creatinine levels in urine were measured in 128 Danish inhabitants by ICP-MS in order to establish reference intervals of molybdenum in urine for the Danish population as a part of the EURO-TERVIHT project (Trace Element Reference Values in Human Tissues).
The Mo concentration was determined using the isotopes 95Mo and 98Mo.
The values measured based on 98Mo were about 2% lower than those calculated using 95Mo, a negligible difference in the context of reference values.
The limit of detection was 0.2 mug I-1, the precision was 8.6% and the recovery of added NIST 1643c certified reference material was 94%. The distribution of the data, with and without correction for creatinine concentration, was log-normal.
The mean concentration measured was 42.5 mugI-1, (3.89 mug Mo mmol-1 creatinine) using 95Mo and 41.5 1 mugI-1 (3.81 mug Mo mmol-1 creatinine) using 98Mo, with the 95% parametric reference intervals 10.0-124.0 mug l-1 (0.89-11.50 mug Mo mmol-1 creatinine) and 9.6-122.6 mug l-1 (0.84-11.47 mug Mo mmol-1 creatinine), respectively.
The difference between men and women reached the level of significance only after the values were corrected for the creatinine concentration.
There was no influence of age on the Mo concentration.
Specific effects of different food and beverage intakes could not be demonstrated, with the exception of a positive correlation between butter consumption and Mo concentration.
Mots-clés Pascal : Molybdène, Analyse quantitative, Analyse chimique, Taux, Urine, Liquide biologique, Homme, Danemark, Europe, Epidémiologie, Spectrométrie ICP, Spectrométrie masse, Méthode couplée
Mots-clés Pascal anglais : Molybdenum, Quantitative analysis, Chemical analysis, Rate, Urine, Biological fluid, Human, Denmark, Europe, Epidemiology, Inductive coupling plasma spectrometry, Mass spectrometry, Coupled method
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 98-0142554
Code Inist : 002B03L05. Création : 21/07/1998.